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Retinitis pigmentosa
41yoRetinitis pigmentosa (RP) is a progressive genetic disorder characterized by the degeneration of photoreceptor cells, primarily affecting night and peripheral vision. Fundus autofluorescence (FAF) is a key diagnostic tool in monitoring RP, utilizing the natural fluorescence of lipofuscin in the retinal pigment epithelium (RPE) to detect areas of activity and atrophy. FAF imaging helps identify patterns of progression and areas of retinal degeneration, providing crucial insights for assessing disease severity and potential therapeutic responses.
#retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW
Outros Cases
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Ocular albinism
52yoOcular albinism often presents with foveal hypoplasia, characterized by an underdeveloped fovea. Optical Coherence Tomography (OCT) reveals the absence of a foveal pit and a continuous inner retinal layer. This lack of foveal specialization is a hallmark of the condition and contributes to visual acuity deficits. Advanced imaging techniques, including […]
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Diabetic Macular Edema
37yoDiabetic macular edema (DME) with longstanding subretinal fluid (SRF) can lead to hyperautofluorescence on fundus autofluorescence (FAF) imaging. This hyperautofluorescence indicates chronic damage and accumulation of lipofuscin in the retinal pigment epithelium (RPE). It is a potential biomarker of worse prognosis, as it suggests persistent retinal stress and damage. #DME […]
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AMD: Drusenoid PED
74yoIn age-related macular degeneration (AMD), drusenoid pigment epithelial detachment (PED) can be assessed using advanced retinal pigment epithelium (RPE) analysis. This analysis, performed with Optical Coherence Tomography (OCT), provides detailed imaging of the RPE and the drusenoid material. It helps in evaluating the structural integrity of the RPE, the extent […]
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Neovascular AMD
77yoThe early stages of neovascular age-related macular degeneration (AMD) can be challenging to diagnose. Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) are valuable tools in this regard. OCT provides detailed cross-sectional images of retinal layers, revealing subtle fluid accumulation and retinal thickening. OCTA detects abnormal blood flow, […]
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AMD: Drusenoid PED
74yoIn age-related macular degeneration (AMD), drusenoid pigment epithelial detachment (PED) can be effectively visualized using the green channel in color fundus photography. The green channel enhances the contrast, highlighting the drusenoid material and providing detailed imaging of the PED. This helps in assessing the extent and progression of the disease. […]
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Foveal hypoplasia
32yoFoveal hypoplasia grade 1a is characterized by the absence of a foveal pit while retaining the inner retinal layers at the fovea. Optical Coherence Tomography (OCT) reveals the absence of the typical foveal depression and a continuous inner retinal layer. Optical Coherence Tomography Angiography (OCTA) shows an abnormal vascular pattern, […]
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Diabetic macular edema
37yoDiabetic retinopathy is characterized by increased vascular permeability, leading to leakage of blood and fluid into the retina. Fluorescein angiography (FA) is used to assess this permeability, revealing areas of leakage, microaneurysms, and also neovascularization. FA helps in evaluating the extent of retinal damage and guiding treatment decisions. #DiabeticRetinopathy #VascularPermeability […]
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Peripheral Hemorrhagic Exudative Chorioretinopathy
72yoPeripheral hemorrhagic exudative chorioretinopathy (PHECR) is a retinal condition characterized by peripheral hemorrhages and exudation. In the early stage, small hemorrhages and exudates are present. Fundus autofluorescence (FAF) using the green channel can highlight areas of exudation and hemorrhage. Optical Coherence Tomography (OCT) provides detailed cross-sectional images, revealing the extent […]
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Best’s vitelliform dystrophy
36yoBest’s vitelliform dystrophy is characterized by the presence of vitelliform lesions in the macula. Fundus autofluorescence (FAF) imaging shows increased autofluorescence corresponding to the accumulation of lipofuscin within the lesion. Optical Coherence Tomography (OCT) provides cross-sectional images, revealing a hyperreflective lesion between the retinal pigment epithelium (RPE) and the photoreceptor […]
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Hypertensive retinopathy
63yoHypertensive retinopathy is characterized by changes in the retinal vasculature due to high blood pressure. Key features include arteriolar light reflex, where the central light reflex on arterioles is enhanced and appears broader. Arteriovenous (AV) crossing changes, also known as AV nicking, occur when thickened arterioles compress venules at crossing […]
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Sector retinitis pigmentosa
70yoAsymmetric sectorial retinitis pigmentosa (RP) presents with localized retinal degeneration, often confined to specific quadrants of the retina, leading to an asymmetric distribution of visual field loss. Fundus autofluorescence (FAF) imaging reveals sectorial hypoautofluorescence corresponding to areas of RPE atrophy. Optical Coherence Tomography (OCT) shows localized thinning of the retinal […]
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Best’s vitelliform dystrophy
12yoBest’s vitelliform dystrophy progresses from a vitelliform lesion to a “scrambled egg” appearance. Fundus autofluorescence (FAF) highlights the changing autofluorescence patterns as the lesion evolves. Optical Coherence Tomography (OCT) shows the transition from a well-defined subretinal lesion to a more disrupted, heterogeneous structure, reflecting the breakdown of the vitelliform material […]