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Central Areolar Choroidal Dystrophy
88yoCentral Areolar Choroidal Dystrophy (CACD) is a genetic disorder causing progressive atrophy of the central choroid and retinal pigment epithelium (RPE), leading to central vision loss. Autofluorescence imaging highlights RPE damage, showing areas of hypo-autofluorescence. Optical coherence tomography (OCT) reveals thinning of the choroid and RPE atrophy, crucial for monitoring disease progression.
#CACD #ChoroidalDystrophy #Autofluorescence #OCTImaging #RetinaDisorders #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW
Other Cases
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Multifocal Best’s vitelliform dystrophy
33yoMultifocal Best vitelliform dystrophy is a rare retinal condition characterized by multiple yellowish vitelliform lesions scattered across the posterior pole. Fundus autofluorescence (FAF) shows hyperautofluorescent lesions due to lipofuscin accumulation in the retinal pigment epithelium (RPE). Over time, areas of hypoautofluorescence may appear, indicating RPE atrophy. FAF is crucial for […]
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Drusen
37yoThe presence of drusen in a young woman may suggest inherited or systemic conditions rather than typical age-related macular degeneration (AMD). Conditions like familial drusen, basal laminar drusen, or early-onset drusen should be considered. Optical Coherence Tomography (OCT) can reveal their size and location, and fundus autofluorescence (FAF) may show […]
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Polypoidal choroidal vasculopathy
81yoPolypoidal Choroidal Vasculopathy (PCV) should be investigated when subretinal fluid is observed adjacent to the optic disc. Fundus autofluorescence (FAF) is useful in these cases, as it highlights retinal pigment epithelium (RPE) changes. Areas of hyperautofluorescence indicate RPE stress, while hypoautofluorescence suggests atrophy, aiding in the identification of PCV-related abnormalities. […]
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Secondary macular telangiectasia (BRVO)
70yoSecondary macular telangiectasia due to branch retinal vein occlusion (BRVO) is characterized by vascular changes in the macula. Fluorescein angiography (FA) reveals dilated and tortuous macular capillaries, areas of leakage, and capillary telangiectasia. FA helps assess the extent of macular involvement, guiding management decisions such as anti-VEGF therapy to address […]
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Myopic macular neovascularization
40yoMyopic macular neovascularization (MNV) located in the superior parafoveal region can be effectively treated with anti-VEGF therapy. After treatment, the lesion appears as an area of hypoautofluorescence on fundus autofluorescence (FAF), indicating resolution of neovascular activity and associated damage to the retinal pigment epithelium (RPE). FAF is a useful tool […]
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Ocular toxoplasmosis: Chorioretinitis scars
67yoIn ocular toxoplasmosis, chorioretinitis scars can reveal underlying structures such as the posterior long ciliary artery and nerve. These become visible due to the localized atrophy of the retina, retinal pigment epithelium (RPE), and choroid, allowing clearer visualization of the deeper scleral and vascular structures. #Toxoplasmosis #ChorioretinitisScar #PosteriorCiliaryArtery #RetinaImaging #FAF […]
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Macular telangiectasia type 2
82yoMacular Telangiectasia Type 2 (MacTel 2) can be monitored with blue light reflectance imaging, which highlights areas of retinal degeneration and structural changes. Over a 1-year follow-up, an increase in the hyperreflectant area indicates disease progression, reflecting the expansion of retinal abnormalities. This imaging modality is crucial for tracking disease […]
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Rhegmatogenous retinal detachment
56yoIn macula-off rhegmatogenous retinal detachment, post-surgical recovery can be evaluated using Optical Coherence Tomography (OCT). An excellent recovery of the external retina is characterized by the restoration of the ellipsoid zone (EZ) and external limiting membrane (ELM). These findings on OCT are associated with better visual outcomes, indicating effective surgical […]
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Sickle cell retinopathy
20yoIn sickle cell disease, the Goldberg classification is used to stage sickle cell retinopathy and guide treatment: Stage I: Peripheral arteriolar occlusion. Stage II: Peripheral arteriovenous anastomoses. Stage III: Sea fan neovascularization. Stage IV: Vitreous hemorrhage. Stage V: Tractional or rhegmatogenous retinal detachment. Treatment is typically initiated at Stage III […]
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AMD: Geographic atrophy
87yon age-related macular degeneration (AMD) with geographic atrophy (GA), fundus autofluorescence (FAF) and near-infrared (NIR) reflectance imaging provide complementary insights. FAF reveals hypoautofluorescence in areas of RPE loss, with hyperautofluorescent borders indicating regions at risk for progression. NIR reflectance highlights the atrophic zones with high contrast, providing detailed visualization of […]
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Lamellar Hole-Associated Epiretinal Proliferation,
72yoLamellar Hole-Associated Epiretinal Proliferation (LHEP) can be differentiated from conventional epiretinal membranes (ERM) using blue light reflectance imaging. ERM appears hyperreflectant, while LHEP is hyporeflectant. This distinction arises due to macular pigment intermixed within LHEP, which absorbs blue light. Blue light reflectance is a valuable tool for distinguishing these conditions […]
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Presumed Cone Dystrophy
44yoCone dystrophy is characterized by progressive dysfunction of cone photoreceptors, leading to visual symptoms such as photophobia, color vision loss, and central vision decline. Fundus autofluorescence (FAF) often shows a bull’s-eye pattern of hyper- and hypoautofluorescence, indicating retinal pigment epithelium (RPE) changes. Optical Coherence Tomography (OCT) reveals thinning or disruption […]