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Sickle cell retinopathy
15yoIn sickle cell retinopathy, peripheral ischemia occurs due to the occlusion of small retinal blood vessels by sickle-shaped red blood cells, which have decreased flexibility and increased adhesion to vascular endothelium. These blockages cause oxygen deprivation in the peripheral retina, leading to tissue hypoxia, neovascularization (e.g., sea fan formations), and potential complications like vitreous hemorrhage and retinal detachment if left untreated.
#SickleCellRetinopathy #PeripheralIschemia #Pathophysiology #RetinaImaging #Hypoxia #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW
Other Cases
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Vitreomacular traction: Spontaneous release
60yoVitreomacular traction (VMT) occurs when the vitreous exerts abnormal traction on the macula. Spontaneous release can occur as the vitreous detaches completely, relieving the traction. Optical Coherence Tomography (OCT) is critical for identifying VMT and documenting its resolution, showing the absence of traction and restoration of normal macular contour after […]
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AMD: Geographic atrophy
96yoIn age-related macular degeneration (AMD) with geographic atrophy (GA), en-face OCT imaging reveals areas of hypertransmission through the atrophic regions. This hypertransmission results from increased light penetration through the loss of retinal pigment epithelium (RPE) and outer retinal layers, providing detailed visualization of the extent and shape of atrophic zones. […]
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AMD: Geographic atrophy
87yoIn age-related macular degeneration (AMD) with geographic atrophy (GA), fundus autofluorescence (FAF) and near-infrared reflectance (NIR) imaging are essential tools. FAF highlights hypoautofluorescent areas corresponding to RPE loss and hyperautofluorescent borders indicating regions at risk for progression. NIR provides high-contrast imaging of atrophic regions and choroidal changes, complementing FAF for […]
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Sickle cell retinopathy
15yoIn sickle cell retinopathy, peripheral ischemia occurs due to the occlusion of small retinal blood vessels by sickle-shaped red blood cells, which have decreased flexibility and increased adhesion to vascular endothelium. These blockages cause oxygen deprivation in the peripheral retina, leading to tissue hypoxia, neovascularization (e.g., sea fan formations), and […]
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Diabetic retinopathy: ERM following PRP
79yoIn proliferative diabetic retinopathy (PDR), panretinal photocoagulation (PRP) is a standard treatment to reduce neovascularization and prevent vision loss. However, PRP may contribute to the formation of an epiretinal membrane (ERM) due to retinal inflammation and scarring. ERM can cause visual distortion and may require surgical peeling if it significantly […]
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Optic disc drusen
64yoOptic disc drusen appear as small, yellowish deposits within the optic nerve head and are visible on fundus examination, often with a lumpy or irregular appearance. These drusen can sometimes simulate optic disc edema, so accurate identification is essential. They may increase the risk of visual field defects and require […]
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Epiretinal membrane
70yoAn epiretinal membrane (ERM) is a thin, fibrous layer that forms on the inner retinal surface, causing visual distortion and blurriness. Optical Coherence Tomography (OCT) shows ERM as a hyperreflective layer on the retina’s inner surface, often with retinal thickening and distortion. Treatment may involve observation or surgical removal (membrane […]
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Peripheral retinoschisis
69Peripheral retinoschisis is a splitting of the retinal layers that can be mistaken for retinal detachment due to similar fundoscopic appearance. However, retinoschisis is generally more stable and lacks the subretinal fluid that characterizes a true detachment. Optical Coherence Tomography (OCT) and careful clinical examination help distinguish between the two, […]
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Degenerative myopia: Tessellated fundus
40In degenerative myopia, a tessellated (or tigroid) fundus appears due to thinning of the retinal pigment epithelium (RPE), which reveals the underlying choroidal vasculature as a mosaic pattern. Red channel imaging enhances the contrast of this pattern, providing clear visualization of these structural changes. #DegenerativeMyopia #TessellatedFundus #RedChannel #RetinaImaging #ChoroidalVasculature #retina […]
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Diabetic macular edema
79yoDiabetic macular edema (DME) is characterized by retinal thickening and fluid accumulation in the macula, often leading to vision loss. Fluorescein angiography (FA) is crucial for evaluating DME, as it reveals areas of capillary leakage, microaneurysms, and zones of ischemia. This imaging helps to assess the extent of vascular damage, […]
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AMD: Geographic atrophy
89In age-related macular degeneration (AMD) with geographic atrophy, fundus autofluorescence (FAF) is used to assess the extent of retinal pigment epithelium (RPE) loss. Areas of atrophy appear as hypoautofluorescent zones due to the absence of RPE, while hyperautofluorescent borders may indicate regions at risk for progression. FAF is essential for […]
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Proliferative Sickle cell retinopathy
15In proliferative sickle cell retinopathy, fluorescein angiography (FA) is crucial for identifying areas of peripheral ischemia and neovascularization, particularly the characteristic “sea fan” neovascular formations. FA highlights areas of non-perfusion and leakage, helping to map the extent of ischemia and guide interventions such as laser photocoagulation to prevent complications like […]