Tag:
Drusen

The presence of drusen in a young woman may suggest inherited or systemic conditions rather than typical age-related macular degeneration (AMD). Conditions like familial drusen, basal laminar drusen, or early-onset drusen should be considered. Optical Coherence Tomography (OCT) can reveal their size and location, and fundus autofluorescence (FAF) may show associated retinal pigment epithelium (RPE) changes. Proper evaluation is essential to distinguish from more serious retinal diseases.

#Drusen #InheritedDrusen #YoungPatient #FAF #OCT #RetinaImaging #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

In age-related macular degeneration (AMD), clinical findings includes confluent soft drusen, pigment migration, and RPE atrophy. Confluent soft drusen are large, yellowish deposits under the RPE, indicating a higher risk of progression. Pigment migration occurs as RPE cells move irregularly, and RPE atrophy presents as areas of cell loss, all contributing to gradual vision loss.

#AMD #SoftDrusen #PigmentMigration #RPEAtrophy #RetinaImaging #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

In age-related macular degeneration (AMD), drusen and drusenoid pigment epithelial detachment (PED) are common findings. Optical Coherence Tomography (OCT) reveals drusen as hyperreflective elevations between the retinal pigment epithelium (RPE) and Bruch’s membrane, while drusenoid PED appears as larger sub-RPE accumulations. Fundus autofluorescence (FAF) highlights areas of RPE stress with hyperautofluorescence, and atrophy with hypoautofluorescence, helping to monitor progression.

#AMD #Drusen #DrusenoidPED #OCT #FAF #RetinaImaging #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

Check out this case: A 73-year-old male presented with apparent non-neovascular age-related macular degeneration (AMD) in the right eye. True color imaging revealed multiple confluent soft drusen across the macular area. FAF-green imaging showed hypoautofluorescent spots over some of these drusen. SD-OCT B-scan images clearly depicted the drusen as homogeneous, medium-to-high reflectivity elevations of the retinal pigment epithelium (RPE). Advanced RPE analysis enabled precise evaluation of the area and volume of these drusen, facilitating intuitive comparisons over time. However, a more detailed analysis using OCTA revealed type 3 macular neovascularization with adjacent subtle intraretinal fluid. This case underscores the importance of thorough evaluation in AMD patients, utilizing all tools in multimodal retinal imaging for the early detection of more severe forms.

#retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία  #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

Type 3 macular neovascularization (MNV) in age-related macular degeneration (AMD) is characterized by neovascular growth within the retinal layers. Optical Coherence Tomography Angiography (OCTA) effectively visualizes these intraretinal neovascular networks. Anti-VEGF therapy is the primary treatment, reducing neovascular activity and associated fluid to preserve vision.

#Type3MNV #AMD #OCTA #AntiVEGF #retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

Type 3 macular neovascularization (MNV) is characterized by neovascular growth originating from the deep capillary plexus, extending into the retinal layers. This subtype, also known as retinal angiomatous proliferation (RAP), can be effectively visualized using Optical Coherence Tomography Angiography (OCTA). OCTA provides detailed imaging of the retinal and choroidal microvasculature, facilitating the detection of abnormal blood flow. Intraretinal fluid is commonly associated with Type 3 MNV and can indicate disease progression or response to treatment.

#retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία  #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

Drusen regression in age-related macular degeneration (AMD) can precede the emergence of geographic atrophy (GA). As drusen, which are lipid deposits beneath the retina, decrease in size or number, there may be increased exposure of underlying retinal tissue to damage, potentially accelerating GA development.

#retina #oftalmo #ophthalmology #oftalmologia #oftalmología #ophtalmologie #офтальмологія #офтальмология #οφθαλμολογία  #retinography2024 #CIRRUS6000 #CLARUS700 #ZEISSRETINAWORKFLOW

Disclosure: All images featured in this post were acquired and analyzed using devices integrated within the Zeiss Retina Workflow. This ensures high-quality, detailed visual data for comprehensive assessment.

True color and RGB channels in a case of cuticular drusen.

Disclosure: All images featured in this post were acquired and analyzed using devices integrated within the Zeiss Retina Workflow. This ensures high-quality, detailed visual data for comprehensive assessment.

True color, green and red channels in a case of age-related macular degeneration presenting soft confluent drusen.

Disclosure: All images featured in this post were acquired and analyzed using devices integrated within the Zeiss Retina Workflow. This ensures high-quality, detailed visual data for comprehensive assessment.